by dr. John j. pierce, do acoep, abaarm



It is truly an exciting time in history, as scientists get closer to the ever-elusive concept of the “fountain of youth.”  And, as oftentimes it occurs during a search for one remedy, other promising possibilities are found.  This may hold true with the drug, Metformin, the first-line treatment for Type 2 Diabetes.  

While Metformin is the most widely prescribed anti-diabetic drug in the world, scientists have found possibilities in its use as an anti-aging pill.

Currently, two studies testing Metformin and its possible protection against multiple diseases of aging are in process:  

TAME ‘‘Targeting Aging with Metformin’’

The TAME study will use Metformin to study biological aging, which may hopefully lead to the discovery of even better drugs to prevent aging-related diseases, which include cardiovascular disease, type II diabetes, osteoarthritis, osteoporosis, cancer, Alzheimer’s disease and other dementias.

MILES “Metformin in Longevity”

This study has already been completed at the Institute for Aging Research at Albert Einstein College of Medicine, and the health industry is excited to learn of its results, which have not been published as of yet.  Metformin was investigated as to its possibilities as a treatment to genetically restore the blood sugar levels of older adults with elevated blood sugar (impaired glucose tolerance – IGT) to that of younger subjects with healthy blood sugar levels.  

If data shows Metformin to actually alter the biology of aging in tissues to a younger profile, scientists may have tapped into one of the world’s first concepts of the fountain of youth, with a possible widespread use of the drug as an anti-aging treatment.

As fad diets deceptively promise to restore you to your teenage weight, drugs can often be mistakenly seen as a panacea.  And it can’t be emphasized enough that a lifetime of unhealthy lifestyle and abuse to your body cannot so easily be remedied with just one pill.  Nothing can ever replace the most beneficial methods to truly live a long, vital life:  regular exercise and healthy nutrition.

Dr. John J. Pierce, D.O. • Ageless Forever Anti-Aging and Longevity Clinic located at

6020 S. Rainbow Blvd. Suite C  Las Vegas, NV 89118 • 702-838-1994 •



HEPATITIS C WITH ONLY 4-WEEK TREATMENTJust two injections of RG-101, in combination with a four-week course of direct-acting antiviral (DAA) therapy, has been shown to clear Hepatitis C in patients at both 12 and 24 weeks after treatment in the majority of patients, according to research presented recently at The Liver Meeting.  

Hepatitis C (HCV) is a liver disease commonly spread through blood.  RG-101 is a newly developed therapy, delivered through injection that specifically targets the microNRA in the liver that is essential for HCV to continue to replicate (or stay active) in a person’s body. 


Here are the symptoms:

1. Intrusive thoughts, such as repeated, involuntary memories;  distressing dreams;  or flashbacks of the traumatic event.

2. Avoiding people, places, activities, objects and situations that bring on distressing memories.  Avoiding talking about what happened or how you feel about it.

3. Negative thoughts and feelings may include ongoing and distorted beliefs about oneself or others (e.g., “I am bad” “No one can be trusted”);  ongoing fear, horror, anger, guilt or shame;  much less interest in activities previously enjoyed;  or feeling detached or estranged from others.

4. Arousal and reactive symptoms may include being irritable and having angry outbursts;  behaving recklessly or in a self-destructive way;  being easily startled;  or having problems concentrating or sleeping.



The Vote is In. No: 4,553,833 (53.94%)  Yes: 3,888,895 (46.06%)

The adult film industry got their word out loud and clear in California on November 8th.  Most adult films are produced in Los Angeles’ San Fernando Valley, along with a great deal starting to be produced in Las Vegas.  In November 2012, Los Angeles approved Measure B, which required pornography actors to wear condoms on set.  (Cal/OSHA) requires condom use during sex in pornographic films, but it is not really enforced, as this requirement is in response to complaints, which there usually are none.  

Proposition 60 would have required adult film producers to provide condoms and make sure that performers use them during scenes in which actors engage in vaginal or anal sex.  This is where things getting sticky.  Almost all performers in today’s market are producers as well, as they produce their own content for websites, clip stores, trade, etc.  While condoms would have not been needed to be visible in films distributed to consumers, producers would have needed to prove that condoms were used.  The bill also contained language that would allow anyone watching a film that the performers were not having protected sex to sue the producer of the film, and access the legal names and addresses of the performers.  This essentially would open up all performers/producers to potential lawsuits, fines and loss of privacy.  The costs of performers’ workplace-related medical examinations, sexually-transmitted infections (STI) tests, and STI vaccines would have been covered by film producers under the measure, where they are now the responsibility of the performer.  

The AIDS Healthcare Foundation run by Michael Weinstein, who built a job for himself into the proposal, contributed approximately $5 million dollars to the proposal, while their opponents, organized as the Coalition Against Worker Harassment, received $545,719.  The California DNC, GOP, Green Party and Libertarian Party all opposed the measure.

Dr. Pierce asks: "What's in your Male Enhancement Supplement?"


By Dr. John J. Pierce, DO ACOEP, ABAARM



It feels great to be the Don Juan of lovers—but many men may not be aware that many sexual enhancement supplements contain ingredients that could pose a risk to their health.  

Men should take caution and be vigilant to choose a SAFE and HEALTHY product that fits their needs, by learning which added ingredients to avoid, so as to not put their health at risk.

The FDA has been actively pursuing investigations on the male enhancement products for years and warns consumers against using certain OTC supplements, which contain the following undeclared drugs:

Sildenafil: The active ingredient found in Viagra (a drug prescribed for erectile dysfunction).  
! This drug can cause symptoms like headache and flushing, and can interact with medications containing nitrates such as nitroglycerine, resulting in dangerously low blood pressure.  Men with diabetes, high blood pressure, high cholesterol, or heart disease often take nitrates. Sulfoaildenafil, Thiosildenafil, Desmethyl carbodenafil and Hydroxythiohomosildenafil are all similar to Sildenafil and its ! Caution.

Tadalafil: The active ingredient found in Cialis (a drug prescribed for erectile dysfunction).
! This drug can cause symptoms like headache and flushing, and can interact with medications containing nitrates such as nitroglycerine, resulting in dangerously low blood pressure.  Men with diabetes, high blood pressure, high cholesterol, or heart disease often take nitrates.

Dapoxetine: A selective serotonin reuptake inhibitor (SSRI) (a drug to treat depression). 
! Dapoxetine has not been approved by the FDA. SSRI drugs are associated with serious side effects including suicidal thinking, abnormal bleeding, and seizures, and can interact with other common medications such as aspirin and ibuprofen, which can cause ventricular arrhythmia or sudden death.

FDA’s National Health Fraud Coordinator, Gary Coody, R. Ph., warns men of the many sexual enhancement products which have been found to contain undeclared drugs or other potentially harmful ingredients such as prescription antidepressants, diuretics and other drugs. All Public Warnings and Recalls of these supplements are available at Consumers who have purchased any of the recalled supplements and/or those with issued warnings should discontinue use immediately and contact their healthcare provider if they have experienced any adverse side effects. Both healthcare providers and consumers are encouraged to report any adverse reactions to dietary supplements to the FDA’s “MedWatch Adverse Event Reporting Program”. For continued monitoring of all supplemental products visit: 

I help many patients find natural alternatives to pharmaceutical drugs at my Ageless Forever clinic, through careful analysis of each patient’s bloodwork. 

Dr. John J. Pierce, D.O. • Ageless Forever Anti-Aging and Longevity Clinic located at 6020 S. Rainbow Blvd. Suite C Las Vegas, NV 89118 • 702-838-1994 •

ANABOLIC STEROIDS - You've Amped Up, Now What?


By Dr. John J. Pierce, D.O.



In order to boost physical performance, many athletes have used anabolic steroids over the years. But with today’s definition of “perfectly fit”—it is the non-athletes who make up an even larger portion of those who have been self-prescribing hormones to improve their physique and appearance. An estimated 2.9 to 4.0 million Americans (age 13-50) have used anabolic steroids, and most without physician supervision, using underground black market resources and products. This is not only medically ill-advised as potentially dangerous, but the purity of the product is greatly questionable, adding extra risk to one’s health.  

Other added dangers are increased by a common method of “stacking” (using two or more anabolic steroids—often androgens) in progressively increasing doses in intermittent cycles. This practice makes it hard to predict the cumulative potential health consequences—not to mention that anabolic steroids are not natural to the body, as they are synthetic man-made compounds. Testosterone is the opposite—it is produced naturally by the body, and is necessary physiologically for health and wellbeing. Anabolic steroids are not, and they can come with negative side effects including damaging both the heart and liver, causing high blood pressure, depression, shrinking of the testicles, erectile and sexual dysfunction and infertility, enlarged breasts (aka “bitch tits”), and negatively affecting cholesterol and blood fat levels.

The practice of “cycling” is based on the notion that drug holidays (intermittent use of anabolic steroids followed by taking a break) may prevent desensitization to large doses of androgen (even though this concept remains to be proven scientifically). Yet after a cycle of anabolic steroid use, testosterone levels may fall to unnaturally low levels (even within a female range), known as anabolic steroid-induced hypogonadism, and it can cause loss of sexual desire and sexual function, depression and even hot flushes, all of which can last sometimes up to four years. These symptoms of withdrawal can be so difficult to tolerate that many men go back on another cycle of anabolic steroids, causing a vicious cycle known as “hooked-on-hormones” syndrome.

Post Cycle Therapy helps to restore natural hormonal function for those who have self-administered anabolic steroids, in order to prevent hypogonadism-induced health consequences, such as loss of muscle and bone mineral mass, sexual and reproductive dysfunction, and depression, as well as to promote healthy aging. Treatment involves various dosages of medications in order to achieve balance once again, as there is no “one-size-fits-all” post-cycle therapy. Therefore it is of utmost importance to find a doctor who is well-versed in andrology (the science of man) and endocrine regulation, as well as the side effects of anabolic steroids. Yet, most physicians tend to be uncomfortable and are hesitant to treat patients who have used anabolic steroids.  

Dr. Pierce at Ageless Forever Anti-Aging Clinic in Las Vegas, Nev., understands the importance of listening to patients so that they feel open to discuss their cycles, stacks and motives, in order to properly diagnose and treat them to bring them back to a balanced and healthy state once again. As a former athlete himself, Dr. Pierce understands the mentality of anabolic steroid users and has educated himself in not only the underground lingo, but also in the newest medical research on the subject, to better provide the best possible individualized care for his patients.

Dr. John J. Pierce, D.O. • Ageless Forever Anti-Aging and Longevity Clinic located at
6020 S. Rainbow Blvd. Suite C Las Vegas, NV 89118 • 702-838-1994 •




One of the most popular training techniques to build muscle is PHA Training (Peripheral Heart Action). This method works as an all-in-one training program that burns fat, boosts cardio and builds muscle all at the same time.

To PHA train, choose five-to-six low intensity exercises that include both upper and lower workouts. Alternate between the upper and lower by completing 15 reps of each maneuver before moving onto the next (but without any breaks—at all!). Implement PHA and you will surprisingly gain more muscle.

The University of São Paulo performed a study that showed PHA as effective in growing bigger biceps and a rock solid core. Former Mr. Universe, Bob Galda swore by PHA Training—and he beat out Schwarzenegger!

HARD TIME FOCUSING? Top Concentration Killers



Multitasking – If you pride yourself in mastering the art of multitasking—STOP. Research shows that during your attention shift from one task to another, you actually lose time. 

Depression – Sadness may seem like the biggest sign of depression, but difficulty concentrating is one of the most common symptoms. Feeling indifferent, hopeless or empty? See a doctor. Depression is highly treatable.

Social Media – Every status update kills your train of thought. Try logging in during work breaks only, to avoid the steady stream of posts that interrupt your concentration during work.

Email – Email can feel like an itch that you’ve just got to scratch, sucking up your concentration with every reply. Schedule time slots in your workday for answering emails, then simply shut it down for a completely focused rest of your work day. 

Cell Phone – More disruptive is the time-consuming distraction of cell phone calls. Utilize caller-ID, let it go to voicemail, unless it’s urgent, and schedule specific times to listen to all messages at one sitting, rather than disruptively throughout the day.

Boredom – Boring tasks can lead to temptation of reaching for your phone or a quick surf of the Internet. Instead, reward yourself after staying on task for a certain period of time, by taking a short coffee or snack break, or better yet, a quick walk outside. 

Stress – The vicious cycle of stress: piles just get bigger when you are having a hard time focusing, and lack of focus tends to make the workload pile up. It shows up in headaches, tight shoulders, even a racing heart. Learn stress reduction techniques. Meditation has been proven to increase your ability to focus. 

Nagging Thoughts – If you’re worried about anything other than work, (an argument yesterday with your spouse, holiday plans and more) it can be almost impossible to focus on work at hand. Make a list. By writing down your distractions you can now separate yourself, and let them go for a while.

Fatigue – Too little sleep has been proven to be an attention killer, as well as short-term memory zapper. Get 7-9 hours of sleep each night and schedule your most difficult tasks during your most alert times of the day.

Hunger – Skipping meals will kill your ability to focus, but breakfast is the most important—and lacking this meal is a top concentration killer.

ADHD – Consistent trouble focusing, with attention problems as a kid, may be the condition known as Attention Deficit Hyperactivity Disorder. If you experience a short attention span with consistent difficulty focusing on tasks, see a doctor. There are ways to ease the symptoms through behavioral therapy and medications.

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